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Six Shooter – Strain Information

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Six Shooter is a powerful hybrid cannabis strain that has gained popularity for its high potency, fast growth, and strong effects. Known for its impressive THC content and balanced genetic lineage, this strain is a favorite among both recreational and medical users. In this guide, we will explore the origins, characteristics, effects, medical and recreational uses, and the scientific aspects of Six Shooter in great detail.

Origins and Genetics

Six Shooter is a hybrid strain developed by Fast Buds, a well-known cannabis seed company specializing in autoflowering genetics. The strain is a result of a careful cross between two potent parent strains:

  • Crystal Meth – A high-THC autoflower strain known for its cerebral stimulation and euphoric effects.
  • Mexican Airlines – A sativa-dominant autoflower strain famous for its energetic and uplifting effects.

The result is an autoflowering hybrid with a balanced 60% sativa and 40% indica ratio, delivering a well-rounded experience that blends euphoria with relaxation.

Appearance, Aroma, and Flavor Profile
six shooter appearance
Appearance

Six Shooter is visually striking, featuring:

  • Large, elongated buds covered in a thick layer of trichomes, giving it a frosty, crystal-like appearance.
  • Deep green foliage with bright orange pistils, enhancing its visual appeal.
  • Dense, resin-coated flowers, making it an excellent choice for concentrate production.
Aroma

The strain’s terpene profile produces a strong and unique scent, blending:

  • Citrus notes (lemon, lime)
  • Pine and earthiness
  • Hints of pepper and spice
Flavor

The flavor of Six Shooter follows its aromatic profile, delivering:

  • Sharp citrus taste, often compared to lemon or lime zest.
  • Woody and earthy undertones.
  • A spicy aftertaste, reminiscent of black pepper.
THC, CBD, and Cannabinoid Profile
THC Content

Six Shooter is known for its high THC content, averaging between 18-23%, making it a highly potent strain. Some phenotypes may even reach 26% THC under optimal growing conditions.

CBD Content
  • CBD levels in Six Shooter are relatively low, usually below 0.5%, meaning it is not ideal for users specifically seeking high-CBD strains.
Other Cannabinoids
  • CBG (~1%): Contributes to anti-inflammatory and neuroprotective effects.
  • CBC (~0.5%): May aid in pain relief and mood stabilization.
Scientific Breakdown: Terpene Profile

The rich terpene profile of Six Shooter contributes to its distinct effects and therapeutic benefits. Key terpenes include:

1. Myrcene (~0.5-1%)
  • Found in mangoes, myrcene enhances relaxation and sedative effects.
  • Acts as an anti-inflammatory and analgesic.
2. Limonene (~0.8-1.2%)
  • A dominant terpene responsible for the strain’s citrus aroma.
  • Known for its mood-enhancing and anti-stress properties.
3. Pinene (~0.3-0.6%)
  • Provides a piney aroma and may help with bronchodilation and respiratory function.
  • Has potential cognitive-enhancing effects.
4. Caryophyllene (~0.6-1%)
  • Contributes to the spicy, peppery flavor.
  • Binds to CB2 receptors, giving it anti-inflammatory and pain-relieving properties.
Methods of Ingestion & Their Scientific Impact
A. Smoking (Combustion)
  • Bioavailability: ~30% (varies based on individual metabolism)
  • Onset: 1-5 minutes
  • Peak Effects: 15-30 minutes
  • Duration: 2-4 hours
  • Metabolism Pathway: Pulmonary absorption (lungs → bloodstream → brain)
  • Ideal for: Rapid relief of pain, stress, anxiety, and immediate recreational effects.

Science Behind It:

  • When cannabis is smoked, the THC is vaporized at ~157°C (315°F), allowing rapid absorption through the alveoli in the lungs.
  • The cannabinoids bypass first-pass metabolism in the liver, leading to immediate psychoactive effects.
  • Terpenes like myrcene enhance THC absorption, potentially intensifying effects.

Drawbacks:

  • Loss of cannabinoids due to combustion (~30-50%).
  • Formation of harmful byproducts (e.g., tar, carbon monoxide).
  • Respiratory irritation over long-term use.
B. Vaping (Convection/Conduction Heating)
  • Bioavailability: ~50-80%
  • Onset: 2-10 minutes
  • Peak Effects: 20-40 minutes
  • Duration: 3-5 hours
  • Metabolism Pathway: Pulmonary absorption
  • Ideal for: Maximum THC efficiency with reduced lung irritation.

Science Behind It:

  • Vaporization heats cannabis at a lower temperature (typically 160-220°C (320-428°F)), preventing combustion but still activating cannabinoids.
  • Higher bioavailability compared to smoking, meaning more THC is absorbed per dose.
  • Vaping preserves terpenes, maintaining flavor and enhancing the entourage effect.

Drawbacks:

  • Requires specialized equipment (dry herb or oil vaporizers).
  • Possible health concerns related to vape additives in oil-based cartridges.
C. Edibles (Gastrointestinal Absorption)
  • Bioavailability: ~4-12% (due to first-pass metabolism)
  • Onset: 30-90 minutes
  • Peak Effects: 2-4 hours
  • Duration: 6-12 hours (can extend to 24 hours in high doses)
  • Metabolism Pathway: Liver metabolism → 11-hydroxy-THC
  • Ideal for: Long-lasting effects for pain, anxiety, and sleep disorders.
six shooter drink

Science Behind It:

  • THC is metabolized by the liver into 11-hydroxy-THC, a more potent psychoactive metabolite that crosses the blood-brain barrier more effectively.
  • Effects last much longer than inhalation, making edibles useful for chronic pain and sleep disorders.
  • Fat-soluble nature of THC means absorption is increased when consumed with high-fat foods (e.g., butter, oils).

Drawbacks:

  • Delayed onset which may cause excessive intake.
  • Difficult dosage control due to variation in metabolism.
D. Sublingual Tinctures (Oral Mucosa Absorption)
  • Bioavailability: ~40-60%
  • Onset: 15-45 minutes
  • Peak Effects: 60-90 minutes
  • Duration: 4-6 hours
  • Metabolism Pathway: Sublingual absorption → bloodstream (partial bypass of first-pass metabolism)
  • Ideal for: Faster absorption than edibles with longer-lasting effects than smoking/vaping.

Science Behind It:

  • Absorption occurs through the mucous membranes under the tongue, allowing THC to enter the bloodstream directly.
  • Bypassing some of the liver metabolism results in a more predictable and controlled onset than edibles.
  • Carrier oils (MCT oil, coconut oil) improve bioavailability.

Drawbacks:

  • Some bitter taste if not flavored.
  • Less immediate effect compared to smoking or vaping.
E. Topical Application (Transdermal)
  • Bioavailability: Varies (depends on formulation & skin permeability)
  • Onset: 15-60 minutes
  • Duration: 4-8 hours
  • Metabolism Pathway: Transdermal absorption (does not typically enter the bloodstream)
  • Ideal for: Localized pain relief and inflammation.

Science Behind It:

  • Topical creams, balms, and lotions infused with Six Shooter cannabinoids interact with CB2 receptors in the skin.
  • Does not produce psychoactive effects (unless formulated as a transdermal patch with penetration enhancers).
  • Effective for arthritis, muscle pain, and inflammation.

Drawbacks:

  • Not effective for systemic effects unless in transdermal patches.
Onset, Peak, and Duration Across Methods
MethodOnsetPeak EffectsTotal Duration
Smoking1-5 min15-30 min2-4 hours
Vaping2-10 min20-40 min3-5 hours
Edibles30-90 min2-4 hours6-12 hours
Sublingual15-45 min60-90 min4-6 hours
Topical15-60 minN/A (localized)4-8 hours
Factors Affecting Onset & Duration

Several variables influence how Six Shooter cannabis affects individuals, including:

A. Metabolism & Individual Physiology
  • Faster metabolism → Quicker onset but shorter duration.
  • Slower metabolism → Delayed onset but prolonged effects.
B. THC Concentration & Dose
  • Higher THC levels (~26%) in Six Shooter lead to more potent effects.
  • Microdosing (2-5mg THC) leads to milder, functional effects.
C. Tolerance & Frequency of Use
  • Regular users metabolize THC faster, leading to shorter duration and weaker effects over time.
  • Tolerance breaks (T-breaks) can restore sensitivity to THC.
D. Presence of Terpenes
  • Myrcene: Enhances THC absorption, reducing onset time.
  • Limonene: Boosts mood effects and may extend the high.
  • Caryophyllene: Works with CB2 receptors, reducing inflammation.
Effects of Six Shooter Cannabis Strain

Six Shooter provides a fast-acting, intense high that is long-lasting. The effects are a combination of both sativa and indica traits.

1. Recreational Effects
  • Euphoria (Sativa Influence): Users report a rapid onset of happiness and a sense of well-being.
  • Energy Boost: Enhances motivation and focus, making it great for creative activities.
  • Relaxation (Indica Influence): As the high progresses, a wave of calmness spreads through the body.
  • Sociability: Users often feel more talkative and social, making it great for social gatherings.
  • Psychedelic Effects: At high doses, it can cause mild visual distortions and heightened sensory perception.
2. Potential Negative Effects
  • Dry mouth and dry eyes (common side effects of high-THC strains).
  • Dizziness or paranoia in users sensitive to THC.
  • Increased heart rate in some individuals, which may not be suitable for those with cardiovascular conditions.
Medical Benefits of Six Shooter

Despite its high THC and low CBD content, Six Shooter has numerous therapeutic applications.

six shoote med
1. Pain Relief
  • Due to its high THC and caryophyllene content, Six Shooter is effective for chronic pain, muscle spasms, and migraines.
2. Stress and Anxiety Reduction
  • The presence of limonene helps reduce stress, anxiety, and symptoms of PTSD.
  • However, in some cases, excessive use may increase anxiety due to its high THC potency.
3. Depression and Mood Disorders
  • The euphoric effects make it beneficial for individuals suffering from depression and mood disorders.
4. Appetite Stimulation
  • Six Shooter is known to induce strong hunger cravings, making it useful for patients dealing with appetite loss due to chemotherapy or eating disorders.
5. Insomnia
  • In higher doses, the relaxing indica effects can help individuals with insomnia or difficulty sleeping.
Cultivation and Growing Information
1. Genetic Considerations & Seed Selection
  • Six Shooter is an autoflowering hybrid, meaning it does not rely on light cycles to flower.
  • Seeds should be sourced from reputable breeders like Fast Buds to ensure genetic stability and high germination rates.
  • Ideal Phenotypes: Growers typically select phenotypes with high trichome production and dense bud structure.
Key Genetic Traits
  • THC Potential: Up to 26% (under optimal conditions).
  • Autoflowering Cycle: Completes from seed to harvest in 9-10 weeks.
  • Height & Growth Pattern: Can grow up to 1.4 meters (4.5 feet), taller than most autoflowers.
six shooter cultivation
2. Optimal Environmental Conditions

Scientific research on cannabis cultivation has identified precise environmental conditions that maximize growth:

Temperature & Humidity
Growth StageTemperature Range (°C)Humidity (%)
Seedling22-26°C65-75%
Vegetative22-28°C50-60%
Flowering20-26°C40-50%
Late Flowering18-24°C30-40%
  • High humidity in early stages promotes strong root development.
  • Lower humidity in flowering prevents mold and bud rot.
Lighting Requirements
  • Indoor Cultivation: Best under LED or HPS lights (600W or more).
  • Light Spectrum:
    • Seedling & Veg: Blue spectrum (400-500nm) for compact, bushy growth.
    • Flowering: Red spectrum (620-780nm) for enhanced bud production.
  • Light Schedule: 18/6 (18 hours light, 6 hours dark) is ideal, but since Six Shooter is autoflowering, it can also thrive under a 24/0 cycle.
3. Soil vs. Hydroponics: Which Is Better?
A. Soil Cultivation
  • Best for flavor development due to rich terpene synthesis.
  • Recommended organic super soil mix:
    • 50% Coco Coir (for aeration and water retention).
    • 25% Compost or Worm Castings (rich in microbes and nutrients).
    • 15% Perlite (improves drainage).
    • 10% Bat Guano / Mycorrhizae (natural fertilizers).
B. Hydroponic Systems

Hydroponics increases THC content and yield due to direct nutrient uptake.

SystemBenefits
DWC (Deep Water Culture)Rapid root growth, high oxygen levels.
Ebb and FlowControlled nutrient delivery, good for medium-scale grows.
AeroponicsMost efficient, but requires precision in humidity & pH levels.
  • Hydroponic pH: 5.5 – 6.0
  • Soil pH: 6.0 – 6.5
  • Hydroponics requires constant EC (electrical conductivity) monitoring to ensure nutrient balance.
4. Nutrient Requirements for Maximum Yield

Six Shooter has high nutrient demands, particularly for nitrogen, phosphorus, and potassium (N-P-K).

Ideal Feeding Schedule

Growth StageN-P-K RatioKey Nutrients
Seedling2-1-2Humic acids, root boosters
Vegetative4-2-3High nitrogen (N), calcium, magnesium
Early Flowering2-4-5Phosphorus (P) for bud development
Late Flowering1-4-5Potassium (K) for resin production
  • Silica Supplements: Strengthens stems and increases bud density.
  • Micronutrients: Calcium (Ca), Magnesium (Mg), Sulfur (S) are essential for trichome production.
  • Avoid Overfeeding: Excess nitrogen in flowering can inhibit bud development.
5. Training Techniques for High Yields
Low-Stress Training (LST)
  • Tying down branches increases light exposure and improves bud development.
  • Best done early in vegetative stage to shape plant structure.
Screen of Green (SCROG)
  • Uses a horizontal net to spread branches evenly.
  • Maximizes yield per square meter, especially in indoor grows.
Defoliation (Selective Leaf Removal)
  • Removing lower fan leaves improves airflow and redirects energy to buds.
  • Avoid excessive defoliation to prevent stress in autoflowers.
6. Flowering & Harvest Optimization
Flowering Period (Week 6-10)
  • Keep PPFD (Photosynthetic Photon Flux Density) at 800-1000 µmol/m²/s for max THC production.
  • Monitor for pest infestations (spider mites, aphids).
Flushing (Week 9-10)
  • Use pure water (pH 6.0) for the last 7-10 days.
  • Purpose: Removes residual nutrients, enhances flavor.
Harvesting Timing
  • Trichome Check: Use a 60x microscope to inspect trichomes.
    • Milky White Trichomes → Peak THC levels.
    • Amber Trichomes → More sedative effects.
  • Best Time to Harvest: When 70% trichomes are milky, 30% amber.
7. Post-Harvest Processing
Drying (7-10 Days)
  • Ideal Conditions: 18-22°C, 50-60% humidity.
  • Slow Drying Prevents: Harsh taste, chlorophyll retention.
  • Air Circulation: Use oscillating fans, but avoid direct airflow on buds.
Curing (2-4 Weeks)
  • Store buds in airtight glass jars.
  • Open jars daily for 10-15 minutes in the first week to release excess moisture.
  • Enhances flavor, potency, and smoothness.
8. Enhancing THC & Terpene Content
CO₂ Enrichment
  • Increasing CO₂ levels to 1200-1500 ppm during flowering boosts yield and potency.
UV-B Exposure
  • UV-B light (280-315nm) exposure increases trichome production and THC synthesis.
  • Best used in last 2 weeks of flowering.
Conclusion

Six Shooter is a well-balanced hybrid strain that offers powerful effects, high yields, and medical benefits. Its fast growth cycle, rich terpene profile, and high THC content make it a top choice among cannabis enthusiasts. Whether you seek pain relief, stress reduction, or a boost in creativity, this strain delivers a well-rounded and enjoyable experience.

Key Takeaways
  • Genetics: Crystal Meth × Mexican Airlines
  • THC: 18-26% | CBD: <0.5%
  • Effects: Euphoric, relaxing, energetic, creative
  • Medical Uses: Pain relief, stress, anxiety, depression, appetite stimulation
  • Best for: Recreational enjoyment, medical treatment, social interactions
  • Growing: 9-10 weeks, high-yielding autoflower

Six Shooter is a must-try for those looking for a potent, flavorful, and high-yielding strain. Always start with a low dose, especially for new users, to avoid potential THC-related side effects.

For a complete directory of cultivars, visit our Cannabis Strain Reviews.