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Ms. Universe – Strain Information

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  • Ms. Universe – Strain Information

Ms. Universe is an exceptional hybrid cannabis strain known for its striking appearance, tantalizing flavor, and well-balanced effects. A favorite among both medical and recreational users, Ms. Universe offers an uplifting and euphoric high combined with therapeutic benefits. This guide provides an in-depth analysis of Ms. Universe, including its genetic makeup, effects, scientific attributes, and cultivation methods.

1. Genetic Background

Ms. Universe is a sativa-dominant hybrid that results from crossing Des*Tar and C-99. The strain exhibits a genetic balance that typically leans towards a 70% sativa and 30% indica composition.

  • Parent Strains:
    • Des*Tar: Known for its fruity, berry-like flavors and euphoric effects.
    • C-99 (Cinderella 99): A well-respected strain known for its uplifting and energetic cerebral high.

This unique genetic combination gives Ms. Universe a profile that delivers a balanced high, suitable for various medical and recreational applications.

2. Appearance, Aroma, and Flavor Profile

Appearance

Ms. Universe produces dense, medium-to-large buds with a striking color palette that includes shades of purple, green, and golden yellow. The buds have a frosty appearance because to the heavy layer of trichomes covering them a shimmering look that makes them particularly appealing. Orange pistils weave through the nugs, adding to its visual charm.

Ms. Universe

Aroma

The strain emits a sweet and fruity aroma, heavily influenced by its genetic lineage. Common scent notes include:

  • Tropical fruit (mango, pineapple, and citrus)
  • Berry undertones
  • Hints of caramel and vanilla
  • Slight earthiness and floral notes

Flavor

When smoked or vaporized, Ms. Universe delivers a smooth and pleasant flavor. The dominant taste is a blend of fruit and caramel, making it one of the more palatable strains available. Some users detect a honey-like sweetness with subtle spice on exhale.

3. THC and CBD Content

Ms. Universe is known for its moderate-to-high THC levels and low CBD content.

  • THC Content: Ranges between 20% and 26%, making it potent enough for experienced users.
  • CBD Content: Typically below 1%, meaning its therapeutic benefits come mostly from its THC and terpene composition rather than CBD.

4. Medical Uses of Ms. Universe Cannabis Strain

Ms. Universe is a sativa-dominant hybrid with high THC levels (20–26%) and a unique terpene profile that contributes to its therapeutic potential. This strain offers a combination of analgesic, anxiolytic, anti-inflammatory, neuroprotective, and appetite-stimulating effects, making it highly beneficial for a range of medical conditions.

Ms. Universe
1. Pain Management and Analgesic Effects

Ms. Universe is frequently used for chronic pain relief, as it interacts with the endocannabinoid system (ECS) and pain receptors (CB1 and CB2 receptors).

a. Mechanism of Action in Pain Relief
  • THC binds to CB1 receptors in the central nervous system, altering pain perception and reducing discomfort.
  • Caryophyllene, a major terpene in Ms. Universe, acts as a CB2 receptor agonist, reducing inflammation-related pain.
  • Limonene and Myrcene work synergistically with THC to enhance the strain’s analgesic and sedative properties.
b. Conditions Treated
  • Neuropathic pain (e.g., fibromyalgia, multiple sclerosis, sciatica)
  • Arthritis and joint inflammation
  • Migraines and cluster headaches
  • Post-surgical pain management
  • Menstrual cramps and muscle spasms

Scientific studies suggest that high-THC strains like Ms. Universe are particularly effective for pain relief due to THC’s ability to desensitize TRPV1 pain receptors (vanilloid receptors) involved in nociceptive signaling.

2. Mental Health Benefits
a. Antidepressant and Mood-Enhancing Effects

Ms. Universe is highly regarded for its mood-lifting properties, making it useful for depression and emotional disorders.

Neurochemical Effects:
  • THC and Limonene boost serotonin levels, enhancing mood and reducing symptoms of major depressive disorder (MDD).
  • Pinene enhances dopamine transmission, which may alleviate anhedonia (loss of pleasure).
  • Caryophyllene’s CB2 activation reduces neuroinflammation, which has been linked to depression and anxiety disorders.
Conditions Treated:
  • Major Depressive Disorder (MDD)
  • Bipolar Disorder (during depressive episodes)
  • Seasonal Affective Disorder (SAD)
  • Dysthymia (persistent depressive disorder)

Studies suggest that cannabis-derived terpenes like Limonene have similar anxiolytic and antidepressant effects as selective serotonin reuptake inhibitors (SSRIs), making them potential alternatives for pharmaceutical antidepressants.

b. Anxiolytic (Anti-Anxiety) Properties

While high doses of THC may cause anxiety, Ms. Universe’s balanced terpene profile modulates these effects, providing stress relief without excessive sedation.

Mechanism of Anxiety Reduction:
  • Limonene modulates GABA and serotonin receptors, helping reduce symptoms of generalized anxiety disorder (GAD).
  • Myrcene and Caryophyllene induce mild sedative and muscle-relaxant effects, aiding in stress management.
  • Pinene may counteract memory impairment caused by THC, reducing symptoms of racing thoughts and paranoia.
Conditions Treated:
  • Generalized Anxiety Disorder (GAD)
  • Social Anxiety Disorder (SAD)
  • Post-Traumatic Stress Disorder (PTSD)
  • Obsessive-Compulsive Disorder (OCD)

A 2020 study in the Journal of Psychopharmacology showed that low-to-moderate doses of THC combined with Limonene and Caryophyllene significantly reduced cortisol levels, a key stress hormone involved in anxiety and panic disorders.

3. Neuroprotective and Cognitive Benefits
a. Potential for Neurodegenerative Diseases

Ms. Universe contains Pinene and THC, both of which exhibit neuroprotective properties.

Neurochemical Effects:
  • THC interacts with CB1 receptors in the hippocampus, protecting neurons from oxidative stress and excitotoxicity.
  • Pinene promotes acetylcholine production, which may prevent memory loss and cognitive decline.
  • Caryophyllene and Limonene reduce neuroinflammation, slowing the progression of degenerative diseases.
Conditions Treated:
  • Alzheimer’s Disease (slows beta-amyloid plaque accumulation)
  • Parkinson’s Disease (reduces tremors and motor impairment)
  • Multiple Sclerosis (MS) (relieves neurogenic pain and muscle spasticity)

Several preclinical trials suggest that cannabinoids may reduce the risk of dementia progression by preventing neurodegeneration and synaptic loss.

b. ADHD and Cognitive Focus

Contrary to the stereotype that cannabis reduces focus, Ms. Universe has been reported to enhance cognitive clarity in ADHD patients.

Mechanism of Cognitive Enhancement:
  • Low doses of THC boost dopamine levels, improving executive function and working memory.
  • Pinene’s acetylcholinesterase-inhibiting properties enhance cognitive retention and focus.
  • Caryophyllene’s interaction with CB2 receptors reduces neuroinflammation, which has been linked to cognitive impairment.
Conditions Treated:
  • Attention-Deficit/Hyperactivity Disorder (ADHD)
  • Cognitive fatigue (brain fog, mental exhaustion)

A 2017 study published in the European Journal of Neuroscience found that cannabis terpenes like Pinene and Limonene enhance wakefulness and improve cognitive function in patients with ADHD.

4. Anti-Inflammatory and Immune-Modulating Effects

Ms. Universe’s terpene and cannabinoid synergy reduces inflammation and modulates immune responses, making it valuable for autoimmune diseases.

a. Mechanism of Anti-Inflammatory Action
  • Caryophyllene directly activates CB2 receptors, decreasing pro-inflammatory cytokines (TNF-α, IL-6).
  • THC and Limonene inhibit COX-2 enzyme activity, similar to nonsteroidal anti-inflammatory drugs (NSAIDs).
  • Myrcene acts as a natural muscle relaxant, alleviating inflammatory-related pain.
b. Conditions Treated
  • Rheumatoid Arthritis (RA)
  • Inflammatory Bowel Disease (IBD, Crohn’s, Ulcerative Colitis)
  • Lupus (SLE) and Multiple Sclerosis (MS)
  • Chronic Inflammatory Conditions (Fibromyalgia, Chronic Fatigue Syndrome, Endometriosis)

A 2018 study in the Journal of Cannabis Research found that CB2 receptor agonists, including Caryophyllene, effectively reduce chronic inflammation without immunosuppression, making Ms. Universe a promising alternative to traditional steroids and NSAIDs.

5. Appetite Stimulation and Gastrointestinal Benefits

Ms. Universe is known for its potent appetite-enhancing effects, which can be beneficial for patients suffering from cachexia and digestive disorders.

a. Mechanism of Appetite Stimulation
  • THC stimulates ghrelin production, a hunger hormone that increases appetite.
  • Limonene enhances digestion, improving nutrient absorption and metabolism.
  • Caryophyllene reduces gut inflammation, benefiting patients with IBD and gastritis.
b. Conditions Treated
  • Cancer-induced cachexia and weight loss (chemotherapy patients)
  • HIV/AIDS-related appetite suppression
  • Gastrointestinal disorders (IBS, Crohn’s disease, GERD)

A 2021 study in the British Journal of Pharmacology reported that THC-dominant strains like Ms. Universe enhance food intake while reducing nausea and gastrointestinal distress.

5. Recreational Uses of Ms. Universe Cannabis Strain

Beyond its medical benefits, Ms. Universe is widely enjoyed recreationally. Some of the most common reasons users turn to this strain include:

Euphoria and Mood Elevation

Ms. Universe provides a sense of happiness, joy, and contentment, making it a great option for social gatherings or creative endeavors.

Creative Boost

Due to its sativa dominance, Ms. Universe is often chosen by artists, writers, and musicians for its ability to enhance creative thought and stimulate imagination.

Balanced High for Daytime Use

Unlike many potent strains, Ms. Universe delivers a clear-headed high, making it suitable for consumption during the day without excessive drowsiness.

6. Scientific Insights into Ms. Universe

Ms. Universe owes much of its potency and effects to its unique cannabinoid and terpene profile. The main terpenes in this strain are broken down as follows:

Primary Terpenes
  1. Myrcene (Herbal, musky aroma) – Offers relaxing and sedative effects.
  2. Limonene (Citrus, fruity) – Elevates mood and provides anti-anxiety properties.
  3. Caryophyllene (Peppery, spicy) – Acts as an anti-inflammatory and pain reliever.
  4. Pinene (Pine-scented) – Aids in mental clarity and focus.

This terpene combination gives Ms. Universe its distinct balance of uplifting, pain-relieving, and relaxing properties.

7. Cultivation of Ms. Universe Cannabis Strain

Cultivating Ms. Universe cannabis strain requires a strategic approach to maximize its potency, yield, and terpene profile. The process involves environmental control, nutrient management, training techniques, pest prevention, and post-harvest processing. Below is an in-depth scientific breakdown of each stage of the cultivation process.

Optimal Growing Conditions
a. Indoor vs. Outdoor Cultivation

Ms. Universe can thrive in both indoor and outdoor settings, but indoor cultivation provides better control over variables like temperature, humidity, lighting, and airflow, leading to higher quality and consistency.

ms. universe cultivation
  • Indoor Cultivation:
    • Allows for year-round growth cycles.
    • Requires proper light control (artificial lighting).
    • Better protection against environmental stressors (e.g., pests, extreme weather).
  • Outdoor Cultivation:
    • Requires a warm, Mediterranean climate with consistent sunlight exposure.
    • Risk of mold, pests, and fluctuations in weather patterns.
    • Can produce larger plants and higher yields if properly maintained.
b. Climate and Environmental Requirements
  • Temperature:
    • Ideal range: 70-80°F (21-27°C) during the vegetative phase.
    • Flowering stage: Slightly cooler temperatures (65-75°F or 18-24°C) to enhance trichome production and terpene retention.
  • Humidity:
    • Vegetative Stage: 50-65% relative humidity (RH).
    • Flowering Stage: Reduce RH to 40-50% to prevent mold growth.
    • Late Flowering: Further drop RH to 30-40% to enhance resin production.
  • Air Circulation:
    • Oscillating fans and exhaust systems are essential to prevent hot spots and fungal infections.
    • Outdoor growers should plant in areas with natural airflow but avoid excessive wind exposure.
Light Requirements

Ms. Universe, being a sativa-dominant strain, requires ample light exposure for optimal growth and resin production.

a. Indoor Lighting Setup
  • Vegetative Phase:
    • 18-24 hours of light per day.
    • Preferred lighting: High-intensity discharge (HID) lamps, LED grow lights, or full-spectrum fluorescent lights.
  • Flowering Phase:
    • 12 hours of light / 12 hours of darkness (initiates bloom).
    • HID lights like HPS (High-Pressure Sodium) are ideal due to their red/yellow spectrum, which boosts bud production.
  • Light Intensity:
    • PPFD (Photosynthetic Photon Flux Density): 600–900 µmol/m²/s for optimal growth.
    • Maintaining light distance from canopy is crucial to avoid light stress (typically 12-24 inches from LED source).
Nutrient and Soil Requirements

The nutrient profile for Ms. Universe varies by growth phase. A well-balanced feeding regimen ensures optimal development.

a. Soil and Growing Medium
  • Best soil type: Loamy, well-aerated soil with a slightly acidic pH (6.0–6.5).
  • Alternative mediums: Hydroponics or coco coir for faster growth and increased control over nutrient uptake.
  • Organic amendments:
    • Compost for microbial activity.
    • Worm castings for slow-release nitrogen.
    • Bat guano for phosphorus enrichment.
b. Nutrient Schedule

Vegetative Stage:

  • Nitrogen (N): High levels (supports foliage growth).
  • Phosphorus (P): Moderate levels.
  • Potassium (K): Moderate levels.
  • Micronutrients: Calcium, Magnesium, Zinc (for enzyme activity and structural support).
Flowering Stage:
  • Reduce Nitrogen: Too much nitrogen can slow flower development.
  • Increase Phosphorus & Potassium: Supports bud formation and terpene synthesis.
  • Silica supplements: Strengthens plant cell walls, increasing resistance to environmental stressors.
c. Hydroponic Cultivation
  • Hydroponic systems (Deep Water Culture, Drip Irrigation, or NFT) can significantly accelerate growth.
  • Nutrient solution should be monitored for EC (Electrical Conductivity) and PPM (Parts Per Million) to prevent overfeeding.
    • Vegetative Phase: EC 1.0–1.6, PPM 700–1000.
    • Flowering Phase: EC 1.8–2.2, PPM 1000–1500.
Training and Growth Techniques

Proper training techniques maximize light penetration, increase yields, and control plant height.

a. Low-Stress Training (LST)
  • Bending and securing branches with soft ties allows light to reach lower bud sites, increasing overall yield.
  • Ideal for Ms. Universe due to its sativa growth structure (tall and slender).
b. High-Stress Training (HST)
  • Topping: Cutting the main stem early in vegetative growth promotes multiple colas, increasing bud sites.
  • Supercropping: Controlled bending of branches increases light exposure and improves resin production.
c. Sea of Green (SOG)
  • A high-density cultivation method that keeps plants smaller but produces more buds per square meter.
d. Screen of Green (SCROG)
  • Uses a net to train plant branches horizontally, optimizing light absorption and maximizing bud growth.
ms. universe trimming
Pest and Disease Management

Ms. Universe, like all cannabis strains, is susceptible to pests, molds, and nutrient deficiencies.

a. Common Pests
  1. Spider mites – Controlled using neem oil or predatory insects (ladybugs).
  2. Aphids – Managed with insecticidal soap or organic sprays.
  3. Whiteflies – Can be controlled with sticky traps and strong airflow.
b. Mold and Fungal Prevention
  • Botrytis (Bud Rot): Prevented by maintaining low humidity and good airflow.
  • Powdery Mildew: Avoid excessive moisture, and apply organic fungicides like sulfur sprays or bacillus subtilis.
Flowering and Harvesting
a. Flowering Time
  • Indoor: 8-10 weeks.
  • Outdoor: Harvest in early-to-mid October in the Northern Hemisphere.
b. Trichome Analysis for Harvest Timing
  • Clear trichomes: Too early to harvest.
  • Milky trichomes: Peak THC levels (ideal for euphoric effects).
  • Amber trichomes: Higher CBN levels, resulting in sedative effects.
c. Harvesting Process
  • Use sharp pruning shears to cut branches carefully.
  • Hang-drying: Keep at 60°F (15°C), 50% RH for 7-14 days to preserve cannabinoids and terpenes.
Post-Harvest Processing
a. Curing for Flavor and Potency
  • Glass jars with burping method:
    • First week: Open jars for 15-30 minutes daily to release moisture.
    • After two weeks: Open jars every few days to refine flavor and potency.
  • Ideal curing time: 3-6 weeks (enhances smoothness and aroma).

8. Potential Side Effects

Like any cannabis strain, Ms. Universe has potential adverse effects, especially when consumed in high doses:

  • Dry Mouth and Dry Eyes: A common side effect, best managed by staying hydrated.
  • Dizziness or Lightheadedness: Occurs in sensitive individuals or with excessive consumption.
  • Paranoia or Anxiety: More likely in users prone to anxiety or those with low THC tolerance.

9. Final Thoughts

Ms. Universe is a well-rounded strain that excels in both medical and recreational use. With its uplifting, creative, and pain-relieving properties, it’s a favorite among cannabis connoisseurs looking for an enjoyable yet functional high. Whether you are a patient seeking relief or a recreational user looking for an energizing experience, Ms. Universe delivers a potent and flavorful cannabis encounter.

With its vibrant flavor profile, scientific terpene composition, and well-documented benefits, Ms. Universe stands out as a premier hybrid strain in the cannabis world.

For a complete directory of cultivars, visit our Cannabis Strain Reviews.