Can marijuana lower blood pressure

Can Marijuana Lower Blood Pressure ?

1. Mechanism of Action

• THC (Tetrahydrocannabinol): Causes short-term vasodilation, which can temporarily lower blood pressure, especially in new or infrequent users.
• CBD (Cannabidiol): Has been shown in some studies to reduce resting blood pressure and stress-related spikes by modulating the endocannabinoid and nervous systems.

2. Scientific Evidence

• A 2017 JCI Insight study showed 600 mg of oral CBD significantly lowered blood pressure in healthy adults, both at rest and during stress.
• THC can initially drop blood pressure, but may later cause tachycardia (increased heart rate) or orthostatic hypotension (sudden drop upon standing).
• Chronic use may diminish this hypotensive effect due to tolerance.

3. Method of Use

• Inhalation: Rapid onset, short duration of action.
• Oral ingestion: Delayed onset, longer-lasting effects.
• CBD-dominant products are more consistent for hypotensive action; high-THC products have variable effects.

4. Risks and Considerations

• As a first line of treatment for hypertension, it is not advised.
• May interact with medications like beta-blockers or diuretics.
• May cause dizziness, fainting, or fluctuations in blood pressure, especially in older adults or those with cardiovascular conditions.

5. Conclusion

• Marijuana, particularly CBD, can lower blood pressure in some individuals.
• Effects vary by dose, strain, user tolerance, and health status.
• Use with medical supervision is advised, especially for those with existing heart or blood pressure issues.